Product details
Background:
Cadherin is a kind of adhesion protein which belongs to a transmembrane glycoprotein superfamily. It plays an important role in structural integrity of epithelia. This antibody can detect many isotypes of cadherin.
cadherin [ABT123] mouse mAb
Ucallm_WM1294-50
Price range: $268.00 through $328.00
Specifications
| Target | cadherin pan |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, WB, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 130kD |
| Host Species | Mouse |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Source | |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | ABT123 |
| Immunogen | Synthesized peptide derived from human cadherin-1 AA range:800-882 according to Cadherin-1 |
| Sequence | |
| Specificity | The antibody can recognize many isotypes of cadherin including E-cadherin, N-cadherin, P-cadherin and R-cadherin. In western blotting of A431 and MCF7 cell lysates, the antibody can label a 130 kDa band. |
| Gene Name | CDH1/CDH3/CDH4/CDH6 |
| Protein Name | cadherin |
| Other Name | Cadherin-1; / CAM 120/80; / Epithelial cadherin; / E-cadherin; / Uvomorulin; / CD324; / Cadherin-2; / CDw325; / Neural cadherin; / N-cadherin1 Publication; / CD325; / Cadherin-3; / Placental cadherin; / P-cadherin; / Cadherin-4; / Retinal cadherin; / R-CAD; / R-cadherin; / Cadherin-6; / Kidney cadherin; / K-cadherin; / CDH6 |
| Species | Human |
| Gene ID-1 | |
| Uniprot | P55285;P22223;P12830;P55283 |
| Species.1 | |
| Gene ID-2 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | Cadherin is a kind of adhesion protein which belongs to a transmembrane glycoprotein superfamily. It plays an important role in structural integrity of epithelia. This antibody can detect many isotypes of cadherin. |
| Cellular Localization | Membranous |
| Tissue Expression | Non-neural epithelial tissues. |
| Signaling_pathway | |
| Research Areas | >>Rap1 signaling pathway; / >>Apelin signaling pathway; / >>Hippo signaling pathway; / >>Cell adhesion molecules; / >>Adherens junction; / >>Bacterial invasion of epithelial cells; / >>Pathways in cancer; / >>Endometrial cancer; / >>Thyroid cancer; / >>Melanoma; / >>Bladder cancer; / >>Gastric cancer |
| Function | |
| RRID |
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