Product details
Background:
similarity:Contains 1 BTB (POZ) domain., similarity:Contains 6 Kelch repeats.,
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KLHL22 Monoclonal Antibody
Ucallm_WM0285-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KLHL22 |
| Reactivity | Human |
| Applications | WB, IF, ELISA |
| MW(Calculated) | 72kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | Affinity purification |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 3E12 |
| Immunogen | Purified recombinant fragment of human KLHL22 expressed in E. Coli. |
| Specificity | KLHL22 Monoclonal Antibody detects endogenous levels of KLHL22 protein. |
| Gene Name | KLHL22 |
| Protein Name | Kelch-like protein 22 |
| Other Name | KLHL22; / Kelch-like protein 22 |
| Species | Human |
| Gene ID | 84861 |
| Uniprot | Q53GT1, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q99JN2 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm, cytosol . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Nucleus . Lysosome . Mainly cytoplasmic in prophase and prometaphase. Associates with the mitotic spindle as the cells reach chromosome bi-orientation. Localizes to the centrosomes shortly before cells enter anaphase After anaphase onset, predominantly associates with the polar microtubules connecting the 2 opposing centrosomes and gradually diffuses into the cytoplasm during telophase (PubMed:23455478). Localizes to the nucleus upon amino acid starvation (PubMed:29769719). Relocalizes to the cytosol and associates with lysosomes when amino acids are available (PubMed:29769719). . |
| Tissue Expression | Embryo,Kidney,Liver, |
| Signaling_pathway | |
| Research Areas | |
| Function | similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats., |
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