SKU: WM0387 Categories: ,

PTH Monoclonal Antibody

Price range: $268.00 through $328.00

SKU: WM0387-50
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Specifications

Size50μL/100μL
TargetParathyroid Hormone
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)13kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationAffinity purification
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number4H5
ImmunogenPurified recombinant fragment of human PTH (aa1-115) expressed in E. Coli.
SpecificityPTH Monoclonal Antibody detects endogenous levels of PTH protein.
Gene NamePTH
Protein NameParathyroid hormone
Other NameParathyroid hormone; / PTH; / Parathormone; / Parathyrin
SpeciesHuman
Gene ID5741
UniprotP01270
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue Expression
Signaling_pathwayHuman Diseases >> Immune disease >> Rheumatoid arthritis
Research Areas>>Neuroactive ligand-receptor interaction; / >>Parathyroid hormone synthesis, secretion and action; / >>Endocrine and other factor-regulated calcium reabsorption; / >>Rheumatoid arthritis
FunctionDisease:Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.,Function:PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.,online information:Parathyroid hormone entry,similarity:Belongs to the parathyroid hormone family.,
Please login to post questions
Back to Top
Product has been added to your cart