Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is an E3 ubiquitin-protein ligase that binds with miRNAs and maintains the growth and upkeep of embryonic stem cells. This gene also is involved in the G1-S phase transition of the cell cycle. [provided by RefSeq, Dec 2015],
| Size | 50μL/100μL |
| Target | LIN41 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 95kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | LIN41 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TRIM71 LIN41 |
| Protein Name | Tripartite motif-containing protein 71 (Protein lin-41 homolog) |
| Other Name | |
| Species | Human |
| Gene ID | 131405 |
| Uniprot | Q2Q1W2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q1PSW8, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | D3ZVM4 |
| Cellular Localization | Cytoplasm, P-body . |
| Tissue Expression | Specifically expressed in testis. |
| Signaling_pathway | Human Diseases >> Cancer: overview >> MicroRNAs in cancer |
| Research Areas | >>MicroRNAs in cancer |
| Function | Function:May be involved in controlling the timing of organ formation during development.,induction:Down-regulated by retinoic acid in Tera-2 cells.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 filamin repeat.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 2 B box-type zinc fingers.,similarity:Contains 6 NHL repeats.,tissue specificity:Specifically expressed in testis., |
