SKU: WP3751 Categories: ,

TTLL3 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3751-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTTLL3
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)
MW(Observed)85kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TTLL3 AA range: 357-407
SpecificityThis antibody detects endogenous levels of TTLL3 at Human/Mouse
Gene NameTTLL3 PRO0207
Protein NameTTLL3
Other NameTubulin monoglycylase TTLL3; / HOTTL; / Tubulin--tyrosine ligase-like protein 3
SpeciesHuman
Gene ID26140
UniprotQ9Y4R7,
Species.1Mouse
Gene ID.1101100
Uniprot.1A4Q9E5
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, flagellum axoneme .
Tissue ExpressionExpressed in brain, heart, kidney, testis, liver, lung, muscle, spleen, trachea and colon.
Signaling_pathway
Research Areas
FunctionFunction:Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.,similarity:Belongs to the ARPC4 family.,similarity:Contains 1 TTL domain.,subunit:Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.,
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