SKU: WP4158 Categories: ,

TYY2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4158-100
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Product details

Background:

The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010],

Specifications

TargetTYY2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)41kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TYY2 AA range: 9-59
Sequence
SpecificityThis antibody detects endogenous levels of TYY2 at Human/Mouse/Rat
Gene NameYY2 ZNF631
Protein NameTYY2
Other Name
SpeciesHuman
Gene ID-1404281
UniprotO15391,
Species.1Mouse
Gene ID-2100073351
Uniprot.1Q3TTC2,
Species.2Rat
Gene ID-3
Uniprot.2P0C6P6
Organism-4
Gene ID-4
SwissProt-4
BackgroundThe protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010],
Cellular LocalizationNucleus .
Tissue ExpressionExpressed in kidney, liver, spleen and testis but not in colon.
Signaling_pathwayGenetic Information Processing >> Chromosome >> ATP-dependent chromatin remodeling
Research Areas
FunctionFunction:Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes. May antagonize YY1 and function in development and differentiation.,miscellaneous:The gene encoding this protein appears to have arisen by retrotransposition of the YY1 gene in placental mammals. It is encoded by a single exon found in an intron of the gene Mbtps2.,similarity:Belongs to the YY transcription factor family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in kidney, liver, spleen and testis but not in colon.,
RRID
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