SKU: WP6064 Categories: ,

MLXIP rabbit pAb

Price range: $268.00 through $328.00

SKU: WP6064-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetMLXIP
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)101kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human MLXIP
SpecificityThis antibody detects endogenous levels of MLXIP at Human, Mouse
Gene NameMLXIP BHLHE36 KIAA0867 MIR MONDOA
Protein NameMLX-interacting protein (Class E basic helix-loop-helix protein 36) (bHLHe36) (Transcriptional activator MondoA)
Other Name
SpeciesHuman
Gene ID22877
UniprotQ9HAP2,
Species.1Mouse
Gene ID.1208104
Uniprot.1Q2VPU4
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm . Nucleus . Mitochondrion outer membrane . Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus. .
Tissue ExpressionWidely expressed in adult tissues. Most abundant in skeletal muscle.
Signaling_pathway
Research Areas
FunctionBinds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
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