Product details
Background:
EHD2 rabbit pAb
Ucallm_WP6603-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | EHD2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 60kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human EHD2 |
| Specificity | This antibody detects endogenous levels of EHD2 at Human, Mouse,Rat |
| Gene Name | EHD2 PAST2 |
| Protein Name | EH domain-containing protein 2 (PAST homolog 2) |
| Other Name | |
| Species | Human |
| Gene ID | 30846 |
| Uniprot | Q9NZN4, |
| Species.1 | Mouse |
| Gene ID.1 | 259300 |
| Uniprot.1 | Q8BH64, |
| Species.2 | Rat |
| Gene ID.2 | 361512 |
| Uniprot.2 | Q4V8H8 |
| Cellular Localization | Cell membrane; Peripheral membrane protein; Cytoplasmic side . Membrane, caveola; Peripheral membrane protein; Cytoplasmic side . Endosome membrane; Peripheral membrane protein; Cytoplasmic side . Cytoplasm, cytosol . Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes. . |
| Tissue Expression | Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle. |
| Signaling_pathway | |
| Research Areas | |
| Function | ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes . Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane . |
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