Product details
Background:
C2orf60 rabbit pAb
Ucallm_WP8177-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TYW5 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 35kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C2orf60 |
| Specificity | This antibody detects endogenous levels of C2orf60 at Human, Mouse |
| Gene Name | TYW5 C2orf60 |
| Protein Name | tRNA wybutosine-synthesizing protein 5 (hTYW5) (EC 1.14.11.-) |
| Other Name | |
| Species | Human |
| Gene ID | 129450 |
| Uniprot | A2RUC4, |
| Species.1 | Mouse |
| Gene ID.1 | 68736 |
| Uniprot.1 | A2RSX7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes. |
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