SKU: WP15218 Categories: ,

TRP14 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15218-100
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Product details

Background:

function:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide., PTM:The oxidized protein is reduced by TRXR1., similarity:Belongs to the thioredoxin family., similarity:Contains 1 thioredoxin domain., subunit:Interacts with TRXR1 and DYNLL1/DNCL1., tissue specificity:Ubiquitously expressed in cell lines.,

Specifications

Size50μL/100μL
TargetTRP14
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)13kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:20000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from TRP14 . at AA range: 20-100
SpecificityTRP14 Polyclonal Antibody detects endogenous levels of TRP14 protein.
Gene NameTXNDC17
Protein NameThioredoxin domain-containing protein 17
Other NameTXNDC17; / TXNL5; / Thioredoxin domain-containing protein 17; / 14 kDa thioredoxin-related protein; / TRP14; / Protein 42-9-9; / Thioredoxin-like protein 5
SpeciesHuman
Gene ID84817
UniprotQ9BRA2,
Species.1Mouse
Gene ID.152700
Uniprot.1Q9CQM5
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm .
Tissue ExpressionUbiquitously expressed in cell lines.
Signaling_pathway
Research Areas
FunctionFunction:Disulfide reductase. May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions. Modulates TNF-alpha signaling and NF-kappa-B activation. Has peroxidase activity and may contribute to the elimination of cellular hydrogen peroxide.,PTM:The oxidized protein is reduced by TRXR1.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Interacts with TRXR1 and DYNLL1/DNCL1.,tissue specificity:Ubiquitously expressed in cell lines.,
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