Price range: $268.00 through $328.00
Background:
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014],
| Size | 50μL/100μL |
| Target | THIC |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | 44kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human THIC AA range: 320-370 |
| Specificity | This antibody detects endogenous levels of THIC at Human/Mouse/Rat |
| Gene Name | ACAT2 ACTL |
| Protein Name | THIC |
| Other Name | |
| Species | Human |
| Gene ID | 39 |
| Uniprot | Q9BWD1, |
| Species.1 | Mouse |
| Gene ID.1 | 110460 |
| Uniprot.1 | Q8CAY6, |
| Species.2 | Rat |
| Gene ID.2 | 308100 |
| Uniprot.2 | Q5XI22 |
| Cellular Localization | Cytoplasm, cytosol . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Fatty acid degradation; / >>Valine, leucine and isoleucine degradation; / >>Lysine degradation; / >>Tryptophan metabolism; / >>Pyruvate metabolism; / >>Glyoxylate and dicarboxylate metabolism; / >>Butanoate metabolism; / >>Terpenoid backbone biosynthesis; / >>Metabolic pathways; / >>Carbon metabolism; / >>Fatty acid metabolism; / >>Fat digestion and absorption |
| Function | Catalytic activity:2 acetyl-CoA = CoA + acetoacetyl-CoA.,similarity:Belongs to the thiolase family.,subunit:Homotetramer., |
