Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | TRI11 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 51kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TRI11 AA range: 128-178 |
| Specificity | This antibody detects endogenous levels of TRI11 at Human/Mouse/Rat |
| Gene Name | TRIM11 RNF92 |
| Protein Name | TRI11 |
| Other Name | |
| Species | Human |
| Gene ID | 81559 |
| Uniprot | Q96F44, |
| Species.1 | Mouse |
| Gene ID.1 | 338364 |
| Uniprot.1 | Q99PQ2, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | B1H278 |
| Cellular Localization | Cytoplasm. Nucleus. |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The coiled-coil domain and the B30.2 domain are both necessary for interaction with humanin.,Function:May have E3 ubiquitin ligase activity. May contribute to the regulation of the intracellular level of humanin or humanin-containing proteins through the proteasomal degradation pathway.,similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Binds cytoplasmic tail of integrin alpha-1. Interacts with the humanin peptide.,tissue specificity:Ubiquitous., |
