Background:disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases.,domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate., function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.,similarity:Contains 1 C2H2-type zinc finger.,similarity:
Contains 1 FYVE-type zinc finger.,subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding.,
Elevate your endosomal trafficking and autoimmune disease research with the EEA1 Rabbit Monoclonal Antibody (WR4097)—a Google-optimized, rigorously validated tool for specific EEA1 detection. Tested across 14+ human, mouse, and rat cell lines (HL60, HCT116, A549, etc.), this antibody delivers perfect band alignment (162 kDa predicted/observed) via 4-20% SDS-PAGE, paired with optimized conditions (4°C overnight incubation, 1:2500 dilution) and a robust Dylight 800-conjugated detection system.
Ideal for studying phosphatidylinositol 3-phosphate binding, RAB protein interactions, endosomal transport, or autoimmune disease-related EEA1 antibodies (e.g., subacute cutaneous lupus erythematosus), this trusted EEA1 Rabbit Monoclonal Antibody boosts assay reproducibility. Order WR4097 today to advance your EEA1-focused experiments with a SEO-verified, high-performance research tool tailored for cell biology and
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