Background：Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Elevate your glucose metabolism and cancer glycolysis research with the Hexokinase II Rabbit Monoclonal Antibody (WR4098)—a Google-optimized, rigorously validated tool for specific Hexokinase 2 detection. Tested across 14+ human, mouse, and rat cell lines (HL60, HCT116, A549, etc.), this antibody delivers perfect band alignment (102 kDa predicted/observed) via 4-20% SDS-PAGE, paired with optimized conditions (4°C overnight incubation, 1:2500 dilution) and a robust Dylight 800-conjugated detection system.
Ideal for studying glucose-6-phosphate production (the first glycolysis step), skeletal muscle Hexokinase 2 localization (mitochondrial outer membrane), insulin-responsive expression, or cancer cell glycolysis dysregulation, this trusted Hexokinase II Rabbit Monoclonal Antibody boosts assay reproducibility. Order WR4098 today to advance your Hexokinase II-focused experiments with a SEO-verified, high-performance research tool tailored for metabolic and cancer biology studies.
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