Name: α-tubulin [Acetyl Lys40] Monoclonal Antibody [5H5]
SKU: WM1170
Price: 288 USD
Availability: InStock

α-tubulin [Acetyl Lys40] Monoclonal Antibody [5H5]

Ucallm_WM1170-50

Price range: $288.00 through $368.00

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100μl

50μl

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SKU: WM1170-50

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Product details

Background:
function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain., PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively., similarity:Belongs to the tubulin family., subunit:Dimer of alpha and beta chains.,

Specifications

Size	50μL/100μL
Target	α Tubulin Acetyl Lys40
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF
MW(Calculated)
MW(Observed)	52kD
Host Species	Mouse
Isotype
Conjugate/Modification	acetylate
Recommended Dilution Ratio	WB 1:1000-2000; IHC 1:100-200; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Monoclonal
Clone Number	5H5
Immunogen	Synthetic Peptide of α-tubulin (Acetyl Lys40)
Specificity	α-tubulin (Acetyl Lys40) protein detects endogenous levels of α-tubulin (Acetyl Lys40)
Gene Name	TUBA1B
Protein Name	Tubulin alpha-1B chain (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain)
Other Name	Tubulin alpha-1B chain; / Alpha-tubulin ubiquitous; / Tubulin K-alpha-1; / Tubulin alpha-ubiquitous chain
Species	Human
Gene ID	7277
Uniprot	P68363,
Species.1	Mouse
Gene ID.1
Uniprot.1	P05213,
Species.2	Rat
Gene ID.2
Uniprot.2	Q6P9V9
Cellular Localization	Cytoplasm, cytoskeleton.
Tissue Expression	Brain,Cajal-Retzius cell,Colon,Embryonic kidney,Eye,Fetal brain cortex,Keratinocyte
Signaling_pathway	Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Cell growth and death >> Apoptosis;Cellular Processes >> Cellular community - eukaryotes >> Tight junction;Cellular Processes >> Cellular community - eukaryotes >> Gap junction;Human Diseases >> Neurodegenerative disease >> Alzheimer disease;Human Diseases >> Neurodegenerative disease >> Parkinson disease;Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis;Human Diseases >> Neurodegenerative disease >> Huntington disease;Human Diseases >> Neurodegenerative disease >> Prion disease;Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Research Areas	>>Phagosome; / >>Apoptosis; / >>Tight junction; / >>Gap junction; / >>Alzheimer disease; / >>Parkinson disease; / >>Amyotrophic lateral sclerosis; / >>Huntington disease; / >>Prion disease; / >>Pathways of neurodegeneration - multiple diseases; / >>Pathogenic Escherichia coli infection; / >>Salmonella infection
Function	Function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.,PTM:Undergoes a tyrosination/detyrosination cycle, the cyclic removal and re-addition of a C-terminal tyrosine residue by the enzymes tubulin tyrosine carboxypeptidase (TTCP) and tubulin tyrosine ligase (TTL), respectively.,similarity:Belongs to the tubulin family.,subunit:Dimer of alpha and beta chains.,

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α-tubulin [Acetyl Lys40] Monoclonal Antibody [5H5]

Product details

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α-tubulin [Acetyl Lys40] Monoclonal Antibody [5H5]

Product details

Specifications

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