SKU: WP17688 Categories: ,

14-3-3-pan rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17688-100
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Product details

Background:

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008],

Specifications

Target14-3-3-pan
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)27kD
MW(Observed)30kD
Host SpeciesRabbit
IsotypeIgG
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:1000-2000;ELISA 1:5000-20000
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human 14-3-3-pan
Sequence
SpecificityThis antibody detects endogenous levels of Human, Mouse, Rat 14-3-3-pan
Gene NameYWHAB
Protein Name14-3-3-pan
Alias14-3-3 protein beta/alpha;Protein 1054;Protein kinase C inhibitor protein 1;KCIP-1;[Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Organism-1Human
Gene ID-17529
SwissProt-1P31946;P61981;P27348;P63104;P31947
Organism-2Mouse
Gene ID-254401
SwissProt-2Q9CQV8
Organism-3Rat
Gene ID-356011
SwissProt-3P35213
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.; Vacuole membrane . (Microbial infection) Upon infection with Chlamydia trachomatis, this protein is associated with the pathogen-containing vacuole membrane where it colocalizes with IncG. .
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