ABCAA Polyclonal Antibody
Ucallm_WP0896-50
Price range: $268.00 through $328.00
Product details
Background:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | ABCAA |
| Reactivity | Human |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 169kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1100-1180 |
| Specificity | ABCAA Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ABCA10 |
| Protein Name | ATP-binding cassette sub-family A member 10 |
| Other Name | |
| Species | Human |
| Gene ID | 10349 |
| Uniprot | Q8WWZ4 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Multi-pass membrane protein . |
| Tissue Expression | Widely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract. |
| Signaling_pathway | |
| Research Areas | >>ABC transporters |
| Function | Function:Probable transporter which may play a role in macrophage lipid homeostasis.,induction:Down-regulated by cholesterol loading of macrophages.,similarity:Belongs to the ABC transporter family. ABCA subfamily.,similarity:Contains 2 ABC transporter domains.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle, heart, brain and gastrointestinal tract., |
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