Product details
Background:
The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008],
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ACBG1 rabbit pAb
Ucallm_WP17629-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | ACBG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 80kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ACBG1 AA range: 496-546 |
| Specificity | This antibody detects endogenous levels of ACBG1 at Human/Mouse/Rat |
| Gene Name | ACSBG1 BGM KIAA0631 LPD |
| Protein Name | ACBG1 |
| Other Name | |
| Species | Human |
| Gene ID | 23205 |
| Uniprot | Q96GR2, |
| Species.1 | Mouse |
| Gene ID.1 | 94180 |
| Uniprot.1 | Q99PU5, |
| Species.2 | Rat |
| Gene ID.2 | 171410 |
| Uniprot.2 | Q924N5 |
| Cellular Localization | Cytoplasm . Cytoplasmic vesicle . Microsome . Endoplasmic reticulum . Cell membrane . |
| Tissue Expression | Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary. |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Adipocytokine signaling pathway;Organismal Systems >> Endocrine system >> PPAR signaling pathway |
| Research Areas | >>Fatty acid biosynthesis; / >>Fatty acid degradation; / >>Metabolic pathways; / >>Fatty acid metabolism; / >>PPAR signaling pathway; / >>Adipocytokine signaling pathway |
| Function | Catalytic activity:ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.,Function:Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.,tissue specificity:Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary., |
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