Name: ACO11 Polyclonal Antibody
SKU: WP0827
Price: 268 USD
Availability: InStock

ACO11 Polyclonal Antibody

Ucallm_WP0827-50

Price range: $268.00 through $328.00

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50μl

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SKU: WP0827-100

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Product details

Background:

This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010],

Specifications

Target	ACO11
Reactivity	Human, Mouse
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	66kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Modification
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Source
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 290-370
Sequence
Specificity	ACO11 Polyclonal Antibody detects endogenous levels of protein.
Gene Name	ACOT11 BFIT KIAA0707 THEA
Protein Name	Acyl-coenzyme A thioesterase 11 (Acyl-CoA thioesterase 11) (Acyl-CoA thioester hydrolase 11) (Adipose-associated thioesterase) (Brown fat-inducible thioesterase) (BFIT)
Other Name
Species	Human
Gene ID-1	26027
Uniprot	Q8WXI4,
Species.1	Mouse
Gene ID-2
Uniprot.1	Q8VHQ9
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background	This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010],
Cellular Localization	Mitochondrion matrix . Cytoplasm .
Tissue Expression	Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
Signaling_pathway
Research Areas
Function	Function:Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates.,induction:By cold exposure and repressed by heat exposure.,similarity:Contains 1 START domain.,similarity:Contains 2 acyl coenzyme A hydrolase domains.,tissue specificity:Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.,
RRID

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ACO11 Polyclonal Antibody

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ACO11 Polyclonal Antibody

Product details

Specifications

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