SKU: WP10945 Categories: ,

ADAM32 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10945-100
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Product details

Background:

ADAM metallopeptidase domain 32(ADAM32) Homo sapiens This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],

Specifications

TargetADAM32
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)87kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from ADAM32 . at AA range: 460-540
Sequence
SpecificityADAM32 Polyclonal Antibody detects endogenous levels of ADAM32 protein.
Gene NameADAM32
Protein NameDisintegrin and metalloproteinase domain-containing protein 32
Other NameADAM32; / Disintegrin and metalloproteinase domain-containing protein 32; / ADAM 32
SpeciesHuman
Gene ID-1203102
UniprotQ8TC27,
Species.1Mouse
Gene ID-2
Uniprot.1Q8K410
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
BackgroundADAM metallopeptidase domain 32(ADAM32) Homo sapiens This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],
Cellular LocalizationMembrane; Single-pass type I membrane protein .
Tissue ExpressionTestis specific.
Signaling_pathway
Research Areas
FunctionFunction:May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,tissue specificity:Testis specific.,
RRID
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