SKU: WP10951 Categories: ,

ADAMTS-19 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP10951-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetADAMTS-19
ReactivityHuman, Mouse
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)140kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human ADAMTS19. AA range:251-300
SpecificityADAMTS-19 Polyclonal Antibody detects endogenous levels of ADAMTS-19 protein.
Gene NameADAMTS19
Protein NameA disintegrin and metalloproteinase with thrombospondin motifs 19
Other NameADAMTS19; / A disintegrin and metalloproteinase with thrombospondin motifs 19; / ADAM-TS 19; / ADAM-TS19; / ADAMTS-19
SpeciesHuman
Gene ID171019
UniprotQ8TE59,
Species.1Mouse
Gene ID.1240322
Uniprot.1P59509
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted, extracellular space, extracellular matrix .
Tissue ExpressionExpressed in fetal lung, but not in any adult tissues examined. Expression was detected in an osteosarcoma cDNA library.
Signaling_pathway
Research Areas
Functioncofactor:Binds 1 zinc ion per subunit.,Domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,PTM:The precursor is cleaved by a furin endopeptidase.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 peptidase M12B domain.,similarity:Contains 1 PLAC domain.,similarity:Contains 5 TSP type-1 domains.,tissue specificity:Expressed in fetal lung, but not in any adult tissues examined. Expression was detected in an osteosarcoma cDNA library.,
Please login to post questions
Back to Top
Product has been added to your cart