SKU: WP7720 Categories: ,

ADM2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7720-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetADM2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)16kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ADM2
SpecificityThis antibody detects endogenous levels of ADM2 at Human, Mouse,Rat
Gene NameADM2 AM2
Protein NameADM2 (Intermedin) [Cleaved into: Adrenomedullin-2 (AM2) (Intermedin-long) (IMDL); Intermedin-short (IMDS)]
Other Name
SpeciesHuman
Gene ID79924
UniprotQ7Z4H4,
Species.1Mouse
Gene ID.1223780
Uniprot.1Q7TNK8,
Species.2Rat
Gene ID.2399475
Uniprot.2P61312
Cellular LocalizationSecreted.
Tissue ExpressionExpressed in the esophagus, stomach, jejunum, ileum, ileocecum, ascending colon, transverse colon, descending colon and rectum. Expressed in myocardial cells of the heart, renal tubular cells, hypothalamus, and pituitary.
Signaling_pathwayOrganismal Systems >> Circulatory system >> Vascular smooth muscle contraction
Research Areas
Function[Adrenomedullin-2]: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.; [Intermedin-short]: May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway.
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