SKU: WP4397 Categories: ,

AEBP2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4397-100
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Product details

Background:

Specifications

TargetAEBP2
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)57kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Modification
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human AEBP2 AA range: 155-205
Sequence
SpecificityThis antibody detects endogenous levels of AEBP2 at Human/Mouse
Gene NameAEBP2
Protein NameAEBP2
Other Name
SpeciesHuman
Gene ID-1121536
UniprotQ6ZN18,
Species.1Mouse
Gene ID-211569
Uniprot.1Q9Z248
Species.2
Gene ID-3
Uniprot.2
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular LocalizationNucleus . Localizes to chromatin as part of the PRC2 complex. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionFunction:DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.,sequence Caution:Translated as Gln.,similarity:Belongs to the AEBP2/jing C2H2-type zinc-finger family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Self-associates. Interacts with EED, EZH2, RBBP4 and SUZ12. Component of the PRC2/EED-EZH1 complex, which includes EED, EZH1, SUZ12, RBBP4 and AEBP2 (By similarity). May also interact with RBBP7.,
RRID
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