similarity:Belongs to the AGR family., subunit:Interacts with LYPD3 and alpha-dystroglycan.,
Specifications
Size
50μL/100μL
Target
AGR3
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
MW(Calculated)
19kD
MW(Observed)
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
The antiserum was produced against synthesized peptide derived from human AGR3. AA range:1-50
Specificity
AGR3 Polyclonal Antibody detects endogenous levels of AGR3 protein.
Gene Name
AGR3
Protein Name
Anterior gradient protein 3 homolog
Other Name
AGR3; / BCMP11; / Anterior gradient protein 3 homolog; / AG-3; / AG3; / hAG-3; / Breast cancer membrane protein 11
Species
Human
Gene ID
155465
Uniprot
Q8TD06,
Species.1
Mouse
Gene ID.1
403205
Uniprot.1
Q8R3W7
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Endoplasmic reticulum . Found in the cytoplasm, which could include the endoplasmic reticulum. .
Tissue Expression
Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668). Expression increased with differentiation of airway epithelial cells (PubMed:25751668). Not detected in the mucous cells (PubMed:25751668). Expressed in ciliated cells in the oviduct (PubMed:26170690). Also detected in stomach, colon, prostate and liver (PubMed:25751668). Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690). Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690).
Signaling_pathway
Research Areas
Function
similarity:Belongs to the AGR family.,subunit:Interacts with LYPD3 and alpha-dystroglycan.,