Name: U-Blot® ALDH1A1 Rabbit mAb
SKU: WR4410
Price: 268 USD
Availability: InStock

U-Blot® ALDH1A1 Rabbit mAb

HepG2 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with primary antibody(1:1000). The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

WR4410 HepG2 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with primary antibody(1:1000). The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WR4410-50

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Product details

Background:The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011],

Specifications

Size	50μL/100μL
Target	ALDH1A1
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, IP, ELISA
MW(Calculated)	55kD
MW(Observed)	55kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:500-1:2000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM0629R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	ALDH1A1
Protein Name	Retinal dehydrogenase 1
Other Name	ALDH1A1; / ALDC; / ALDH1; / PUMB1; / Retinal dehydrogenase 1; / RALDH 1; / RalDH1; / ALDH-E1; / ALHDII; / Aldehyde dehydrogenase family 1 member A1; / Aldehyde dehydrogenase, cytosolic
Species	Human
Gene ID	216
Uniprot	P00352,
Species.1	Mouse
Gene ID.1
Uniprot.1	P24549
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm, cytosol . Cell projection, axon .
Tissue Expression	Expressed by erythrocytes (at protein level).
Signaling_pathway
Research Areas	>>Retinol metabolism; / >>Metabolic pathways
Function	Catalytic activity:Retinal + NAD(+) + H(2)O = retinoate + NADH.,Function:Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid.,pathway:Cofactor metabolism; retinol metabolism.,similarity:Belongs to the aldehyde dehydrogenase family.,subunit:Homotetramer.,