SKU: WM0474 Categories: ,

Aldose Reductase Monoclonal Antibody

Price range: $499.00 through $699.00

SKU: WM0474-50
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Product details

Background:
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009],

Specifications

Specification50μL;100μL
TargetAKR1B1
ReactivityHuman, Mouse, Dog, Rabbit
ApplicationsWB
MW(Calculated)36kD
MW(Observed)
Host SpeciesMouse
Isotype
Conjugate
ModificationUnmodified
Recommended Dilution RatioWB 1:1000-1:2000;Not yet tested in other applications.
CompositionLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification ProcessAffinity purification
Puity
Storage Condition-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
ClonalityMonoclonal
Clone Number
ImmunogenPurified recombinant human Aldose Reductase protein fragments expressed in E.coli.
Sequence
SpecificityAldose Reductase Monoclonal Antibody detects endogenous levels of Aldose Reductase protein.
Gene NameAKR1B1
Protein NameAldose reductase
AliasAKR1B1;ALDR1;Aldose reductase;AR;Aldehyde reductase;Aldo-keto reductase family 1 member B1
Organism-1Human
Gene ID-1231
SwissProt-1P15121
Organism-2Mouse
Gene ID-211677
SwissProt-2P45376
Organism-3Rat
Gene ID-3
SwissProt-3P07943
Organism-4
Gene ID-4
SwissProt-4
Cellular LocalizationCytoplasm.
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