SKU: WP2771 Categories: ,

AMGO1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP2771-100
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Product details

Background:

function:Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain., similarity:Belongs to the immunoglobulin superfamily. AMIGO family., similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain., similarity:Contains 6 LRR (leucine-rich) repeats., subcellular location:Associated with axons of neuronal cells., subunit:Binds itself as well as AMIGO2 and AMIGO3.,

Specifications

Size50μL/100μL
TargetAMGO1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)54kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 120-200
SpecificityAMGO1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameAMIGO1 ALI2 AMIGO KIAA1163
Protein NameAmphoterin-induced protein 1 (AMIGO-1) (Alivin-2)
Other Name
SpeciesHuman
Gene ID57463
UniprotQ86WK6,
Species.1Mouse
Gene ID.1
Uniprot.1Q80ZD8,
Species.2Rat
Gene ID.2
Uniprot.2Q80ZD7
Cellular LocalizationCell membrane; Single-pass type I membrane protein . Perikaryon . Cell projection, dendrite . Cell projection, axon . Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal and cortical neurons. Associated with axons of neuronal cells. .
Tissue ExpressionBrain,Hippocampus,Monocytic leukemia,Ovary,
Signaling_pathway
Research Areas
FunctionFunction:Promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain.,similarity:Belongs to the immunoglobulin superfamily. AMIGO family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subcellular location:Associated with axons of neuronal cells.,subunit:Binds itself as well as AMIGO2 and AMIGO3.,
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