Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human AMZ2 AA range: 99-149
Specificity
This antibody detects endogenous levels of AMZ2 at Human/Mouse/Rat
Gene Name
AMZ2 BM-014
Protein Name
AMZ2
Other Name
Species
Human
Gene ID
51321
Uniprot
Q86W34,
Species.1
Mouse
Gene ID.1
13929
Uniprot.1
Q400C8,
Species.2
Rat
Gene ID.2
360650
Uniprot.2
Q400C7
Cellular Localization
Tissue Expression
Down-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS).
Signaling_pathway
Research Areas
Function
Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,enzyme regulation:Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.,Function:Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.,sequence Caution:Translated as Gly.,similarity:Belongs to the peptidase archaemetzincin family.,tissue specificity:Predominantly expressed in heart and testis. Also expressed at lower levels in kidney, liver, pancreas, lung, brain and placenta. Expressed in fetal tissues such as kidney, liver, lung and brain.,