SKU: WP4084 Categories: ,

AMZ2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4084-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetAMZ2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)40kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human AMZ2 AA range: 99-149
SpecificityThis antibody detects endogenous levels of AMZ2 at Human/Mouse/Rat
Gene NameAMZ2 BM-014
Protein NameAMZ2
Other Name
SpeciesHuman
Gene ID51321
UniprotQ86W34,
Species.1Mouse
Gene ID.113929
Uniprot.1Q400C8,
Species.2Rat
Gene ID.2360650
Uniprot.2Q400C7
Cellular Localization
Tissue ExpressionDown-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS).
Signaling_pathway
Research Areas
FunctionCaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,enzyme regulation:Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.,Function:Zinc metalloprotease. Exhibits activity against angiotensin-3 in vitro. Does not hydrolyze either neurogranin or angiotensin-2.,sequence Caution:Translated as Gly.,similarity:Belongs to the peptidase archaemetzincin family.,tissue specificity:Predominantly expressed in heart and testis. Also expressed at lower levels in kidney, liver, pancreas, lung, brain and placenta. Expressed in fetal tissues such as kidney, liver, lung and brain.,
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