SKU: WP17829 Categories: ,

Ankyrin B rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17829-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetAnkyrin B
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)435kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human Ankyrin B
SpecificityThis antibody detects endogenous levels of Ankyrin B at Human, Mouse,Rat
Gene NameANK2
Protein NameAnkyrin B
Other NameAnkyrin-2; / ANK-2; / Ankyrin-B; / Brain ankyrin; / Non-erythroid ankyrin
SpeciesHuman
Gene ID287
UniprotQ01484,
Species.1Mouse
Gene ID.1109676
Uniprot.1Q8C8R3
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton . Membrane . Cytoplasm, myofibril, sarcomere, M line . Apical cell membrane . Cell membrane . Cell junction, synapse, postsynaptic cell membrane . Early endosome . Recycling endosome . Lysosome . Mitochondrion . Cytoplasm, myofibril, sarcomere, Z line . Cell membrane, sarcolemma, T-tubule . Expressed at the apical membrane of airway lung epithelial cells (By similarity). Localized to the plasma membrane of the inner segments of photoreceptors in retina. Colocalizes with SPTBN1 in a distinct intracellular compartment of neonatal cardiomyocytes (PubMed:19007774). In skeletal muscle, localizes to neuromuscular junctions (By similarity). Localizes with puncta at mitochondria ends. Colocalizes and cotransports on motile vesicles with RABGAP1L (By similarity). .
Tissue ExpressionPresent in plasma membrane of neurons as well as glial cells throughout the brain. Expressed in fetal brain and in temporal cortex of adult brain. Also expressed in the inner segments of rod photoreceptors in retina.
Signaling_pathway
Research Areas>>Proteoglycans in cancer
Function
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