Price range: $268.00 through $328.00
Background:
This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | APOBEC3D/F |
| Reactivity | Human, Monkey |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 40kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human APOBEC3D/F. AA range:232-281 |
| Specificity | APOBEC3D/F Polyclonal Antibody detects endogenous levels of APOBEC3D/F protein. |
| Gene Name | APOBEC3D/APOBEC3F |
| Protein Name | Probable DNA dC->dU-editing enzyme APOBEC-3D/F |
| Other Name | APOBEC3D; / Probable DNA dC->dU-editing enzyme APOBEC-3D; / APOBEC3F; / DNA dC->dU-editing enzyme APOBEC-3F; / Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F |
| Species | Human |
| Gene ID | 200316;140564 |
| Uniprot | Q96AK3;Q8IUX4 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm. Cytoplasm, P-body. |
| Tissue Expression | Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung. |
| Signaling_pathway | |
| Research Areas | >>Viral life cycle - HIV-1; / >>Human immunodeficiency virus 1 infection |
| Function | cofactor:Zinc.,Function:Unknown. Unable to reduce HIV-1 infectivity in vitro.,miscellaneous:It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family., |
