SKU: WP7164 Categories: ,

ARHGAP21 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7164-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetARHGAP21
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)215kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human ARHGAP21
SpecificityThis antibody detects endogenous levels of ARHGAP21 at Human, Mouse
Gene NameARHGAP21 ARHGAP10 KIAA1424
Protein NameRho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)
Other Name
SpeciesHuman
Gene ID57584
UniprotQ5T5U3,
Species.1Mouse
Gene ID.171435
Uniprot.1Q6DFV3
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationGolgi apparatus membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
Tissue ExpressionWidely expressed with higher expression in brain, heart, skeletal muscle and placenta.
Signaling_pathway
Research Areas
FunctionFunctions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
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