ARHGAP29 rabbit pAb
Ucallm_WP7356-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ARHGAP29 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 139kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ARHGAP29 |
| Specificity | This antibody detects endogenous levels of ARHGAP29 at Human, Mouse,Rat |
| Gene Name | ARHGAP29 PARG1 |
| Protein Name | Rho GTPase-activating protein 29 (PTPL1-associated RhoGAP protein 1) (Rho-type GTPase-activating protein 29) |
| Other Name | |
| Species | Human |
| Gene ID | 9411 |
| Uniprot | Q52LW3, |
| Species.1 | Mouse |
| Gene ID.1 | 214137 |
| Uniprot.1 | Q8CGF1, |
| Species.2 | Rat |
| Gene ID.2 | 310833 |
| Uniprot.2 | Q5PQJ5 |
| Cellular Localization | |
| Tissue Expression | Widely expressed. Highly expressed in skeletal muscle and heart. Expressed at intermediate level in placenta, liver and pancreas. Weakly expressed in brain, lung and kidney. |
| Signaling_pathway | Cellular Processes >> Cellular community - eukaryotes >> Adherens junction |
| Research Areas | |
| Function | GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis. |
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