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ASIC2 rabbit pAb
Ucallm_WP6853-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | ASIC2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 56kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ASIC2 |
| Specificity | This antibody detects endogenous levels of ASIC2 at Human, Mouse,Rat |
| Gene Name | ASIC2 ACCN ACCN1 BNAC1 MDEG |
| Protein Name | Acid-sensing ion channel 2 (ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) |
| Other Name | |
| Species | Human |
| Gene ID | 40 |
| Uniprot | Q16515, |
| Species.1 | Mouse |
| Gene ID.1 | 11418 |
| Uniprot.1 | Q925H0, |
| Species.2 | Rat |
| Gene ID.2 | 25364 |
| Uniprot.2 | Q62962 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes. . |
| Tissue Expression | Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary. |
| Signaling_pathway | Organismal Systems >> Sensory system >> Inflammatory mediator regulation of TRP channels |
| Research Areas | |
| Function | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate. |
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