Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010],
| Target | ASNS |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 60kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human ASNS AA range: 390-440 |
| Sequence | |
| Specificity | This antibody detects endogenous levels of ASNS at Human/Mouse/Rat |
| Gene Name | ASNS TS11 |
| Protein Name | ASNS |
| Other Name | Asparagine synthetase [glutamine-hydrolyzing]; / Cell cycle control protein TS11; / Glutamine-dependent asparagine synthetase |
| Species | Human |
| Gene ID-1 | 440 |
| Uniprot | P08243, |
| Species.1 | Mouse |
| Gene ID-2 | 27053 |
| Uniprot.1 | Q61024, |
| Species.2 | Rat |
| Gene ID-3 | 25612 |
| Uniprot.2 | P49088 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010], |
| Cellular Localization | cytosol, |
| Tissue Expression | Muscle, |
| Signaling_pathway | |
| Research Areas | >>Alanine, aspartate and glutamate metabolism; / >>Metabolic pathways; / >>Biosynthesis of amino acids |
| Function | Catalytic activity:ATP + L-aspartate + L-glutamine + H(2)O = AMP + diphosphate + L-asparagine + L-glutamate.,pathway:Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-glutamine route): step 1/1.,similarity:Contains 1 asparagine synthetase domain.,similarity:Contains 1 glutamine amidotransferase type-2 domain., |
| RRID |
