SKU: WP11228 Categories: ,

BACH1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP11228-100
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Product details

Background:

This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009],

Specifications

Size50μL/100μL
TargetBACH1
ReactivityHuman, Mouse
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)100kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human BACH1. AA range:131-180
SpecificityBACH1 Polyclonal Antibody detects endogenous levels of BACH1 protein.
Gene NameBACH1
Protein NameTranscription regulator protein BACH1
Other NameBACH1; / Transcription regulator protein BACH1; / BTB and CNC homolog 1; / HA2303
SpeciesHuman
Gene ID571
UniprotO14867,
Species.1Mouse
Gene ID.1
Uniprot.1P97302
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionEpithelium,Placenta,Trachea,
Signaling_pathway
Research Areas
FunctionFunction:Transcriptional regulator that acts as repressor or activator. Binds, in-vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,
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