Product details
Background:
BCO2 rabbit pAb
Ucallm_WP6323-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | BCO2 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 64kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human BCO2 |
| Specificity | This antibody detects endogenous levels of BCO2 at Human, Mouse |
| Gene Name | BCO2 BCDO2 |
| Protein Name | Beta,beta-carotene 9',10'-oxygenase (B-diox-II) (Beta-carotene dioxygenase 2) |
| Other Name | |
| Species | Human |
| Gene ID | 83875 |
| Uniprot | Q9BYV7, |
| Species.1 | Mouse |
| Gene ID.1 | 170752 |
| Uniprot.1 | Q99NF1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Mitochondrion . |
| Tissue Expression | Highly expressed in retinal pigment epithelium. Also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level). |
| Signaling_pathway | |
| Research Areas | |
| Function | Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids. Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond. Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules. |
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