Product details
Background:
BPI rabbit pAb
Ucallm_WP7642-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | BPI |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 54kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human BPI |
| Specificity | This antibody detects endogenous levels of BPI at Human, Mouse,Rat |
| Gene Name | BPI |
| Protein Name | Bactericidal permeability-increasing protein (BPI) (CAP 57) |
| Other Name | |
| Species | Human |
| Gene ID | 671 |
| Uniprot | P17213, |
| Species.1 | Mouse |
| Gene ID.1 | 329547 |
| Uniprot.1 | Q67E05, |
| Species.2 | Rat |
| Gene ID.2 | 296321 |
| Uniprot.2 | Q6AXU0 |
| Cellular Localization | Secreted . Cytoplasmic granule membrane . Membrane-associated in polymorphonuclear Leukocytes (PMN) granules. . |
| Tissue Expression | Restricted to cells of the myeloid series. |
| Signaling_pathway | |
| Research Areas | |
| Function | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |
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