Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human BRUNOL6
Specificity
This antibody detects endogenous levels of BRUNOL6 at Human, Mouse
Gene Name
CELF6 BRUNOL6
Protein Name
CUGBP Elav-like family member 6 (CELF-6) (Bruno-like protein 6) (CUG-BP- and ETR-3-like factor 6) (RNA-binding protein BRUNOL-6)
Other Name
Species
Human
Gene ID
60677
Uniprot
Q96J87,
Species.1
Mouse
Gene ID.1
76183
Uniprot.1
Q7TN33
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus . Cytoplasm .
Tissue Expression
Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney.
Signaling_pathway
Research Areas
Function
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.