C/EBP ζ Polyclonal Antibody
Ucallm_WP11335-50
Price range: $268.00 through $328.00
Product details
Background:
This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML). [provided by RefSeq, Jun 2016],
Specifications
| Size | 50μL/100μL |
| Target | C/EBP ζ |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 120kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CEBPZ. AA range:1-50 |
| Specificity | C/EBP ζ Polyclonal Antibody detects endogenous levels of C/EBP ζ protein. |
| Gene Name | CEBPZ |
| Protein Name | CCAAT/enhancer-binding protein zeta |
| Other Name | CEBPZ; / CBF2; / CCAAT/enhancer-binding protein zeta; / CCAAT-box-binding transcription factor; / CBF; / CCAAT-binding factor |
| Species | Human |
| Gene ID | 10153 |
| Uniprot | Q03701, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P53569 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | Epithelium,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Stimulates transcription from the HSP70 promoter.,similarity:Belongs to the CBF/MAK21 family., |
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