C-TAK1 Polyclonal Antibody
Ucallm_WP11827-50
Price range: $268.00 through $328.00
Product details
Background:
microtubule affinity regulating kinase 3(MARK3) Homo sapiens The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
Specifications
| Size | 50μL/100μL |
| Target | C-TAK1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MARK3. AA range:1-50 |
| Specificity | C-TAK1 Polyclonal Antibody detects endogenous levels of C-TAK1 protein. |
| Gene Name | MARK3 |
| Protein Name | MAP/microtubule affinity-regulating kinase 3 |
| Other Name | MARK3; / CTAK1; / EMK2; / MAP/microtubule affinity-regulating kinase 3; / C-TAK1; / cTAK1; / Cdc25C-associated protein kinase 1; / ELKL motif kinase 2; / EMK-2; / Protein kinase STK10; / Ser/Thr protein kinase PAR-1; / Par-1a; / Serine/threonine-protein kinase p78 |
| Species | Human |
| Gene ID | 4140 |
| Uniprot | P27448, |
| Species.1 | Mouse |
| Gene ID.1 | 17169 |
| Uniprot.1 | Q03141, |
| Species.2 | Rat |
| Gene ID.2 | 170577 |
| Uniprot.2 | Q8VHF0 |
| Cellular Localization | Cell membrane; Peripheral membrane protein . Cell projection, dendrite . Cytoplasm . |
| Tissue Expression | Ubiquitous. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. MARK subfamily.,similarity:Contains 1 KA1 (kinase-associated) domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,tissue specificity:Ubiquitous., |
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