Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human C9orf125
Specificity
This antibody detects endogenous levels of C9orf125 at Human, Mouse,Rat
Gene Name
TMEM246 C9orf125
Protein Name
Transmembrane protein 246
Other Name
Species
Human
Gene ID
84302
Uniprot
Q9BRR3,
Species.1
Mouse
Gene ID.1
67063
Uniprot.1
Q91YV9,
Species.2
Rat
Gene ID.2
362518
Uniprot.2
Q5EB73
Cellular Localization
Golgi apparatus membrane; Multi-pass membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
Function
Golgi-resident glycosylphosphatidylinositol (GPI)-N-acetylgalactosamine transferase involved in the lipid remodeling steps of GPI-anchor maturation. Lipid remodeling steps consist in the generation of 2 saturated fatty chains at the sn-2 position of GPI-anchors proteins . Required for the initial step of GPI-GalNAc biosynthesis, transfers GalNAc to GPI in the Golgi after fatty acid remodeling by PGAP2 .