Specifications
| Target | Calcitonin |
| Reactivity | Human |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 15kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | IHC 1:200-400; IF 1:50-200; ELISA 1:500-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Source | |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | ABT285 |
| Immunogen | Synthesized peptide derived from human Calcitonin AA range: 26-141 |
| Sequence | |
| Specificity | The antibody can specifically recognize human Calcitonin protein. |
| Gene Name | CALCA CALC1 |
| Protein Name | Calcitonin |
| Other Name | Calcitonin [Cleaved into: Calcitonin; / Katacalcin; / Calcitonin carboxyl-terminal peptide; / CCP; / PDN-21; / ] |
| Species | Human |
| Gene ID-1 | 796 |
| Uniprot | P01258 |
| Species.1 | |
| Gene ID-2 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | |
| Cellular Localization | Cytoplasmic |
| Tissue Expression | |
| Signaling_pathway | Organismal Systems >> Circulatory system >> Vascular smooth muscle contraction |
| Research Areas | |
| Function | Function:Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.,Function:CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.,Function:Katacalcin is a potent plasma calcium-lowering peptide.,online information:Calcitonin entry,similarity:Belongs to the calcitonin family., |
| RRID |
