Calretinin [ABT-Calret 1] mouse mAb
Ucallm_WM1642-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
Specifications
| Size | 50μL/100μL |
| Target | Calretinin |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, ELISA |
| MW(Calculated) | 31kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-400; ELISA 1:500-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMM-Calret 1 |
| Immunogen | Recombinant protein |
| Specificity | The antibody can specifically recognize human Calretinin protein. |
| Gene Name | CALB2 CAB29 |
| Protein Name | Calretinin (CR) (29 kDa calbindin) |
| Other Name | |
| Species | Human |
| Gene ID | 794 |
| Uniprot | P22676 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasmic, Nuclear |
| Tissue Expression | Brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Calretinin is a calcium-binding protein which is abundant in auditory neurons.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 6 EF-hand domains.,tissue specificity:Brain., |
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