Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human CAPZA1
Specificity
This antibody detects endogenous levels of CAPZA1 at Human, Mouse,Rat
Gene Name
CAPZA1
Protein Name
F-actin-capping protein subunit alpha-1 (CapZ alpha-1)
Other Name
Species
Human
Gene ID
829
Uniprot
P52907,
Species.1
Mouse
Gene ID.1
12340
Uniprot.1
P47753,
Species.2
Rat
Gene ID.2
691149
Uniprot.2
B2GUZ5
Cellular Localization
Cytoplasm, cytoskeleton .
Tissue Expression
Signaling_pathway
Research Areas
Function
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions.