$499.00
Background:
This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],
| Target | Casein Kinase Iγ1/2/3 |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | 50kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate | |
| Modification | Phospho |
| Recommended Dilution Ratio | IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200 |
| Composition | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification Process | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Purity | |
| Storage Condition | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263. AA range:229-278 |
| Sequence | |
| Specificity | Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263. |
| Gene Name | CSNK1G1/CSNK1G2/CSNK1G3 |
| Protein Name | Casein kinase I isoform gamma-1/2/3 |
| Alias | CSNK1G1;Casein kinase I isoform gamma-1;CKI-gamma 1;CSNK1G2;CK1G2;Casein kinase I isoform gamma-2;CKI-gamma 2;CSNK1G3;Casein kinase I isoform gamma-3;CKI-gamma 3 |
| Organism-1 | Human |
| Gene ID-1 | 53944;1455;1456 |
| SwissProt-1 | Q9HCP0;P78368;Q9Y6M4 |
| Organism-2 | Mouse |
| Gene ID-2 | 214897;103236;70425 |
| SwissProt-2 | |
| Organism-3 | Rat |
| Gene ID-3 | 64086;65278;64823 |
| SwissProt-3 | Q62761;Q62762;Q62763 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Cellular Localization | Cytoplasm. |
