Product details
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Caveolin-3 rabbit pAb
Ucallm_WP7357-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | CAV3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 17kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human Caveolin-3 |
| Specificity | This antibody detects endogenous levels of Caveolin-3 at Human, Mouse,Rat |
| Gene Name | CAV3 |
| Protein Name | Caveolin-3 (M-caveolin) |
| Other Name | |
| Species | Human |
| Gene ID | 859 |
| Uniprot | P56539, |
| Species.1 | Mouse |
| Gene ID.1 | 12391 |
| Uniprot.1 | P51637, |
| Species.2 | Rat |
| Gene ID.2 | 29161 |
| Uniprot.2 | P51638 |
| Cellular Localization | Golgi apparatus membrane; Peripheral membrane protein . Cell membrane; Peripheral membrane protein . Membrane, caveola; Peripheral membrane protein . Cell membrane, sarcolemma . Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). . |
| Tissue Expression | Expressed predominantly in muscle. |
| Signaling_pathway | Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion;Human Diseases >> Neurodegenerative disease >> Prion disease |
| Research Areas | |
| Function | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae . |
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