Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human CCDC62
Specificity
This antibody detects endogenous levels of CCDC62 at Human, Mouse
Gene Name
CCDC62
Protein Name
Coiled-coil domain-containing protein 62 (Protein TSP-NY) (Protein aaa)
Other Name
Species
Human
Gene ID
84660
Uniprot
Q6P9F0,
Species.1
Mouse
Gene ID.1
208908
Uniprot.1
E9PVD1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Nucleus . Mainly nuclear.
Tissue Expression
Highly expressed in adult testis. Expressed in both prostate epithelial and stromal cells, with predominant expression in epithelial cells (at protein level) (PubMed:19126643). Not detected in prostate by RT-PCR (PubMed:19165854). Overexpressed in various cancers.
Signaling_pathway
Research Areas
Function
Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR.