Name: CD172b Polyclonal Antibody
SKU: WP11480
Price: 268 USD
Availability: InStock

CD172b Polyclonal Antibody

Ucallm_WP11480-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP11480-100

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009],

Specifications

Size	50μL/100μL
Target	CD172b
Reactivity	Human
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	48kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; ELISA 1:5000; Not yet tested in other applications.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human SIRPB1. AA range:231-280
Specificity	CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.
Gene Name	SIRPB1
Protein Name	Signal-regulatory protein beta-1
Other Name	SIRPB1; / Signal-regulatory protein beta-1; / SIRP-beta-1; / CD172 antigen-like family member B; / CD antigen CD172b
Species	Human
Gene ID	10326
Uniprot	O00241
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cell membrane; Single-pass type I membrane protein .
Tissue Expression	Detected in monocytes and dendritic cells.
Signaling_pathway	Organismal Systems >> Development and regeneration >> Osteoclast differentiation
Research Areas	>>Osteoclast differentiation
Function	Function:Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.,Function:Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK.,PTM:N-glycosylated.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like C1-type (immunoglobulin-like) domains.,subunit:Interacts with TYROBP. This interaction results in the recruitment of SYK.,tissue specificity:Detected in monocytes and dendritic cells.,