SKU: WP15631 Categories: ,

CD315 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP15631-100
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Product details

Background:

function:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur., sequence caution:Translated as Gln., similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151.,

Specifications

Size50μL/100μL
TargetCD315
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)98kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human PTGFRN. AA range:601-650
SpecificityCD315 Polyclonal Antibody detects endogenous levels of CD315 protein.
Gene NamePTGFRN
Protein NameProstaglandin F2 receptor negative regulator
Other NamePTGFRN; / CD9P1; / EWIF; / FPRP; / KIAA1436; / Prostaglandin F2 receptor negative regulator; / CD9 partner 1; / CD9P-1; / Glu-Trp-Ile EWI motif-containing protein F; / EWI-F; / Prostaglandin F2-alpha receptor regulatory protein; / Prostaglandin F2-alpha receptor-associated protein; / CD315
SpeciesHuman
Gene ID5738
UniprotQ9P2B2,
Species.1Mouse
Gene ID.119221
Uniprot.1Q9WV91,
Species.2Rat
Gene ID.229602
Uniprot.2Q62786
Cellular LocalizationEndoplasmic reticulum membrane; Single-pass type I membrane protein . Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein .
Tissue ExpressionBrain,Embryo,Epithelium,Heart,Liver,PCR rescued clones,
Signaling_pathway
Research Areas
FunctionFunction:Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur.,sequence Caution:Translated as Gln.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with CD9 and CD81. Also seems to interacts with CD63, CD82 and CD151.,
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