Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],
| Size | 50μL/100μL |
| Target | CD83 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 23kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD83. AA range:101-150 |
| Specificity | CD83 Polyclonal Antibody detects endogenous levels of CD83 protein. |
| Gene Name | CD83 |
| Protein Name | CD83 antigen |
| Other Name | CD83; / CD83 antigen; / hCD83; / B-cell activation protein; / Cell surface protein HB15; / CD antigen CD83 |
| Species | Human |
| Gene ID | 9308 |
| Uniprot | Q01151, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | O88324 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Expression | Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.,online information:CD83 antigen,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Monomer.,tissue specificity:Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells., |
